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Accelerating a cure for Long COVID

100 million people suffer from Long COVID — with no approved treatments anywhere in the world. Patients can’t afford to wait.

Treatment Leaderboard

#
Treatment
Stage
Category
Community Rating
1
Pemgarda and Paxlovid
Trial design
Monoclonal antibody, viral replication inhibitor
9
2
Pemgarda and Ensitrelvir
Discovery
Monoclonal antibody, viral replication inhibitor
8
3
Ensitrelvir
Pre-clinical
Long-course antiviral
6
4
Pemgarda
Pre-clinical
Monoclonal antibody
6
5
Metformin
Pre-clinical
Long-course antiviral
5
6
PEG Interferon Lambda
Pre-clinical
Immune modulator
5
7
IVIG
Pre-clinical
Monoclonal antibody
5
8
Evusheld and Paxlovid
Case Study
Monoclonal antibody, viral replication inhibitor
5
9
Paxlovid 
Pilot
Long-course antiviral
4
10
Remdesivir
Study design
Long-course antiviral
3
11
Molnupiravir
Pre-clinical
Long-course antiviral
2
1
Pemgarda and Paxlovid
Trial design
Monoclonal antibody, viral replication inhibitor
9
2
Pemgarda and Ensitrelvir
Discovery
Monoclonal antibody, viral replication inhibitor
8
3
Ensitrelvir
Pre-clinical
Long-course antiviral
6
4
Pemgarda
Pre-clinical
Long COVID Cures
6
5
Metformin
Pre-clinical
Long-course antiviral
5
6
PEG Interferon Lambda
Pre-clinical
Immune modulator
5
7
IVIG
Pre-clinical
Monoclonal antibody
5
8
Evusheld and Paxlovid
Case Study
Monoclonal antibody, viral replication inhibitor
5
9
Paxlovid 
Pilot
Long-course antiviral
4
10
Remdesivir
Study design
Long-course antiviral
3
11
Molnupiravir
Pre-clinical
Long-course antiviral
2
Pemgarda and Paxlovid
Trial design
Monoclonal antibody, viral replication inhibitor
Rank
1
Community Rating
9
Learn More
Pemgarda and Ensitrelvir
Discovery
Monoclonal antibody, viral replication inhibitor
Rank
2
Community Rating
8
Learn More
Ensitrelvir
Pre-clinical
Long-course antiviral
Rank
3
Community Rating
6
Learn More
Pemgarda
Pre-clinical
Long COVID Cures
Rank
4
Community Rating
6
Learn More
Metformin
Pre-clinical
Long-course antiviral
Rank
5
Community Rating
5
Learn More
PEG Interferon Lambda
Pre-clinical
Immune modulator
Rank
6
Community Rating
5
Learn More
IVIG
Pre-clinical
Monoclonal antibody
Rank
7
Community Rating
5
Learn More
Evusheld and Paxlovid
Case Study
Monoclonal antibody, viral replication inhibitor
Rank
8
Community Rating
5
Learn More
Paxlovid 
Pilot
Long-course antiviral
Rank
9
Community Rating
4
Learn More
Remdesivir
Study design
Long-course antiviral
Rank
10
Community Rating
3
Learn More
Molnupiravir
Pre-clinical
Long-course antiviral
Rank
11
Community Rating
2
Learn More
Pemgarda and Paxlovid
Trial design
Monoclonal antibody, viral replication inhibitor
Rank
1
Community Rating
9
Learn More
Pemgarda and Ensitrelvir
Discovery
Monoclonal antibody, viral replication inhibitor
Rank
2
Community Rating
8
Learn More
Ensitrelvir
Pre-clinical
Long-course antiviral
Rank
3
Community Rating
6
Learn More
Pemgarda
Pre-clinical
Monoclonal antibody
Rank
4
Community Rating
6
Learn More
Metformin
Pre-clinical
Long-course antiviral
Rank
5
Community Rating
5
Learn More
PEG Interferon Lambda
Pre-clinical
Immune modulator
Rank
6
Community Rating
5
Learn More
IVIG
Pre-clinical
Monoclonal antibody
Rank
7
Community Rating
5
Learn More
Evusheld and Paxlovid
Case Study
Monoclonal antibody, viral replication inhibitor
Rank
8
Community Rating
5
Learn More
Paxlovid 
Pilot
Long-course antiviral
Rank
9
Community Rating
4
Learn More
Remdesivir
Study design
Long-course antiviral
Rank
10
Community Rating
3
Learn More
Molnupiravir
Pre-clinical
Long-course antiviral
Rank
11
Community Rating
2
Learn More

Have your say

Have a hunch one of these might work, or (even better) tried it yourself? Vote here and add your voice to the conversation.

Unlocking Real-World Evidence

Patients and clinicians are trying off-label medications largely in the dark. Our open datasets amplify these private experiments, so the entire community can benefit.

Surfacing Signal from Noise

We use AI to rapidly reveal treatments that work —turning thousands of fragmented anecdotes into actionable discoveries.

Clinical-grade and thoughtfully designed

We empower patients with validated symptom questionnaires and clinical-quality wearables. Good data at scale means we can see insights faster than traditional research.

And governed by you

We believe in decentralized science. Patients and researchers hold governance tokens in the community, giving them a real voice. It's your data — help us make good decisions on everything from research priorities to ethical IP use.

Are you working on a breakthrough treatment for Long COVID?

There are a few theories about what causes Long COVID. We’re focused on one - viral persistence, or virus that sticks around after the initial infection. If you have ideas for antiviral or immune modulatory approaches to clearing persistent virus, submit them here and we may fund them.

Submit a treatment

Join the mission to accelerate a cure.

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